Triethyl(methoxycarbonylsulfamoyl)aminium → 2-Neopentyl-5-(4-nitrophenyl)-1,3,4-oxadiazole

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of N′-(3,3-dimethylbutanoyl)-4-nitrobenzohydrazide (0.556 g, 1.991 mmol) and methyl N-(triethylammoniumsulfonyl)carbamate (0.572 g, 2.389 mmol) in tetrahydrofuran (10 ml) was heated to 120° C. in a microwave for 45 minutes. The crude reaction mixture was concentrated and purified by normal phase chromatography to give the title compound.

Herkunft & Nachweise