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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873601Generated: October 29, 2026

3-Bromopyridine → (S)-tert-butyl 4-(4-(1-(6-methylpyridazin-3-yl)pyrrolidine-3-carboxamido)phenyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/873601

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
ReactantTert-butyl 4-(4-(azetidine-3-carboxamido)phenoxy)piperidine-1-carboxylateHCID 86702036—
Reactant(S)-tert-butyl 4-(4-(pyrrolidine-3-carboxamido)phenyl)piperidine-1-carboxylateHCID 86702068—
Product(S)-tert-butyl 4-(4-(1-(6-methylpyridazin-3-yl)pyrrolidine-3-carboxamido)phenyl)piperidine-1-carboxylateHCID 86702115—

Reaction Steps

The title compound was prepared as described in Example 1C, substituting 3-bromo-6-methylpyridazine for 3-bromopyridine and (S)-tert-butyl 4-(4-(pyrrolidine-3-carboxamido)phenyl)piperidine-1-carboxylate for tert-butyl 4-(4-(azetidine-3-carboxamido)phenoxy)piperidine-1-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975398B2
Source datasetuspto-grants-2015_03
ORD IDord-d30e125a519e4631ae7dcf2ac000c8fe
Source noteuspto-grants-2015_03