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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873604Generated: October 29, 2026

3-Bromopyridine → Tert-butyl 4-(4-(1-(3-methylpyridazin-4-yl)azetidine-3-carboxamido)phenyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/873604

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
ReactantTert-butyl 4-(4-(azetidine-3-carboxamido)phenoxy)piperidine-1-carboxylateHCID 86702036—
ReactantHCID 86702043HCID 86702043—
ProductTert-butyl 4-(4-(1-(3-methylpyridazin-4-yl)azetidine-3-carboxamido)phenyl)piperidine-1-carboxylateHCID 86702118—

Reaction Steps

The title compound was prepared as described in Example 1C, substituting 4-chloro-3-methylpyridazine for 3-bromopyridine and tert-butyl 4-(4-(azetidine-3-carboxamido)phenyl)piperidine-1-carboxylate for tert-butyl 4-(4-(azetidine-3-carboxamido)phenoxy)piperidine-1-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975398B2
Source datasetuspto-grants-2015_03
ORD IDord-0aa34a44a1384eb18a4266772699edbb
Source noteuspto-grants-2015_03