HCID 117702995, compound → HCID 117702712, compound

HRID 873801Notes

Reaction equation

HRID 873801 reaction equation
[Cl:1][C:2]1[C:7](=[O:8])[N:6]([CH3:9])[CH:5]=[C:4]([NH:10][CH:11]([C:30]2[CH:35]=[CH:34][C:33]([Cl:36])=[CH:32][CH:31]=2)[C:12]2[C:13]([C:27](O)=[O:28])=[N:14][N:15]([CH2:18][C:19]3[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=3)[C:16]=2[CH3:17])[CH:3]=1>C(Cl)Cl.CO>[Cl:1][C:2]1[C:7](=[O:8])[N:6]([CH3:9])[CH:5]=[C:4]([N:10]2[CH:11]([C:30]3[CH:31]=[CH:32][C:33]([Cl:36])=[CH:34][CH:35]=3)[C:12]3[C:13](=[N:14][N:15]([CH2:18][C:19]4[CH:20]=[CH:21][C:22]([O:25][CH3:26])=[CH:23][CH:24]=4)[C:16]=3[CH3:17])[C:27]2=[O:28])[CH:3]=1

Participants

3

Reactant 1

HCID 117702995HCID 117702995, compound

Product 1

HCID 117702712HCID 117702712, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

The title compound was prepared in analogy to the procedure described in Example 1 using 4-((5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-ylamino)(4-chlorophenyl)methyl)-1-(4-methoxybenzyl)-5-methyl-1H-pyrazole-3-carboxylic acid (Step 5.4). tR: 4.74 min (HPLC 1); tR; 1.04 min (LC-MS 2); ESI-MS: 509/511 [M+H]+ (LC-MS 2); Rf=0.64 (CH2Cl2/MeOH 9:1).

Sources & evidence

ORD record
ord-ac927dee49194b4f8cb08ace1ea9ab5f
Source dataset
uspto-grants-2015_03
Patent number
US08975417B2

Reaction notes

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