5-Amino-1,3-dimethyl-1,2-dihydropyridin-2-one → ethyl 4-((4-chlorophenyl)((1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)amino)methyl)-1-(4-methoxybenzyl)-1H-pyrazole-3-carboxylate

Participants

Reaction Steps

The title compound was prepared in analogy to the procedure described in Step 10.3 using ethyl 4-((4-chlorophenyl)(hydroxy)methyl)-1-(4-methoxybenzyl)-1H-pyrazole-3-carboxylate (Step 9.3) and 5-amino-1,3-dimethylpyridin-2(1H)-one (Step 20.2). tR: 4.72 min (HPLC 1); tR: 1.08 min (LC-MS 2); ESI-MS: 521 [M+H]+ (LC-MS 2); Rf=0.16 (EtOAc).

Provenance & Evidence