HCID 117702675, compound → HCID 117702557, compound

HRID 873833Notes

Reaction equation

HRID 873833 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH:26][C:27]2[CH:32]=[C:31]([CH3:33])[C:30](=[O:34])[N:29]([CH3:35])[CH:28]=2)[C:9]2[C:10]([C:23]([OH:25])=O)=[N:11][N:12]([CH2:14][C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)[CH:13]=2)=[CH:4][CH:3]=1>C(Cl)Cl.CO>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[C:9]3[C:10](=[N:11][N:12]([CH2:14][C:15]4[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=4)[CH:13]=3)[C:23](=[O:25])[N:26]2[C:27]2[CH:32]=[C:31]([CH3:33])[C:30](=[O:34])[N:29]([CH3:35])[CH:28]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 117702675HCID 117702675, compound

Product 1

HCID 117702557HCID 117702557, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

The title compound was prepared in analogy to the procedure described in Example 1 using 4-((4-chlorophenyl)((1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)amino)methyl)-1-(4-methoxy-benzyl)-1H-pyrazole-3-carboxylic acid (Step 26.2). tR: 4.40 min (HPLC 1); tR: 1.00 min (LC-MS 2); ESI-MS: 475 [M+H]+ (LC-MS 2); Rf=0.38 (CH2Cl2/MeOH 9:1).

Sources & evidence

ORD record
ord-5a79aac0350f4e5e8bf18a0a7303e440
Source dataset
uspto-grants-2015_03
Patent number
US08975417B2

Reaction notes

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