5-Amino-1,3-dimethyl-1,2-dihydropyridin-2-one → ethyl 4-((4-chlorophenyl)((1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)amino)methyl)-1-cyclopropyl-1H-pyrazole-5-carboxylate

Participants

Reaction Steps

The title compound was prepared in analogy to the procedure described in Step 10.3 using ethyl 4-((4-chlorophenyl)(hydroxy)methyl)-1-cyclopropyl-1H-pyrazole-5-carboxylate (Step 34.3) and 5-amino-1,3-dimethylpyridin-2(1H)-one (Step 20.2). tR: 4.78 min (HPLC 1); tR: 1.10 min (LC-MS 2); ESI-MS: 441 [M+H]+ (LC-MS 2); Rf=0.31 (EtOAc).

Provenance & Evidence