反应详情

The title compound was prepared in analogy to the procedure described in Step 17.3 using 5-hydrazinyl-2,4-dimethoxypyrimidine (Step 46.8) and ethyl 5,5,5-trifluoro-2,4-dioxopentanoate at 100° C. for 2 hr. The crude product was purified by silica gel column chromatography (hexane/30% EtOAc). tR: 1.09 min (LC-MS 2); ESI-MS: 347 [M+H]+ (LC-MS 2); Rf=0.31 (hexane/30% EtOAc).

1. customThe crude product was purified by silica gel column chromatography (hexane/30% EtOAc)