Methylhydrazine → HCID 178428083, compound

Participants

Reaction Steps

The title compound was prepared in analogy to the procedure described for Example 57 using ethyl 2-(4-chlorophenyl)-1-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-4,5-dioxopyrrolidine-3-carboxylate (Step 73.2) and methyl hydrazine at reflux for 32 hr. tR: 0.68 min (LC-MS 2); ESI-MS: 385 [M+H]+, ESI-MS: 383 [M−H]− (LC-MS 2); Rf=0.23 (CH2Cl2/7.5% MeOH/1% AcOH); 1H NMR (400 MHz, DMSO-d6) δ ppm 1.90 (s, 3H) 3.34 (s, 3H) 3.44 (m, 3H) 5.62 (s, 1H) 7.09 (d, J=8.6 Hz, 2H) 7.17-7.34 (m, 3H) 7.60 (d, J=2.7 Hz, 1H).

Provenance & Evidence