N-Ethylpyridine-4-methylamine → HCID 56591618, compound

Participants

Reaction Steps

According to the method of Example 14, 2-(3,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyridine-3-acetic acid and N-(4-pyridinylmethyl)ethylamine were used as raw materials for synthesis, to obtain white solid powder, yield 72.1%. m.p. 250-252° C., ESI-MS m/z: 454[M+H]+, 1H NMR(DMSO-d6, 400 MHz)δ: 1.09(t, 0.7H, J=7.00 Hz), 1.25(t, 2.3H, J=7.00 Hz), 2.57(s, 2.3H), 2.58(s, 0.7H), 3.38(q, 0.5H, J=7.00 Hz), 3.62(q, 1.5H, J=7.00 Hz), 4.32(s, 0.5H), 4.62(s, 1.5H), 4.79(s, 1.5H), 5.02(s, 0.5H), 7.41-7.43(m, 1H), 7.63-7.66(dd, 1H, J=8.40 Hz, 2.24 Hz), 7.79(s, 1H), 7.84-7.87(m, 2H), 7.89-7.90(d, 1H, J=2.24 Hz), 7.96-7.98(d, 1H, J=8.40 Hz), 8.69-8.77(m, 1H), 8.80-8.84(m, 2H).

Provenance & Evidence