N-Ethylpyridine-4-methylamine → HCID 56591904, compound

Participants

Reaction Steps

According to the method of Example 14, 2-(4-chlorophenyl)-6-methylimidazo[1,2-a]pyridine-3-acetic acid and N-(4-pyridinylmethyl)ethylamine were used as raw materials for synthesis, to obtain white solid powder, yield 32.9%. m.p. 229-231° C., ESI-MS m/z: 420[M+H]+, 1H NMR(DMSO-d6, 400 MHz)δ: 1.11(t, 0.6H, J=7.00 Hz), 1.25(t, 2.4H, J=7.00 Hz), 2.47(s, 2.4H), 2.49(s, 0.6H), 3.42(q, 0.4H, J=7.00 Hz), 3.63(q, 1.6H, J=7.00 Hz), 4.25(s, 0.4H), 4.56(s, 1.6H), 4.78(s, 1.6H), 5.01(s, 0.4H), 7.55-7.58(m, 1H), 7.65-7.76(m, 4H), 7.84-7.86(m, 2H), 7.90-7.92(m, 1H), 8.71(s, 1H), 8.80-8.84(m, 2H).

Provenance & Evidence