(2-Hydroxyphenyl)boronic acid → HCID 135867922, compound

HRID 874220Notes

Reaction equation

HRID 874220 reaction equation
Br[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[NH:13][CH:12]=[C:11]2[CH:17]=[O:18].[OH:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1B(O)O>>[OH:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[C:6]1[N:5]=[CH:4][C:3]([C:8]2[CH:9]=[C:10]3[C:14](=[CH:15][CH:16]=2)[NH:13][CH:12]=[C:11]3[CH:17]=[O:18])=[CH:2][CH:7]=1

Participants

3

Reactant 2

HCID 2773454(2-Hydroxyphenyl)boronic acidHCID 86637880HCID 86637880, compound

Product 1

HCID 135867922HCID 135867922, compound

Procedure

The title compound was prepared in analogous manner as described for 2. Thus, starting from 3 (0.1 g, 0.33 mmol) and 2-hydroxy benzeneboronic acid instead of 6-bromo-3-iodopyridineboronic acid following the above described procedure gave 50 mg of pure 4.

Workup

  1. customgave 50 mg of pure 4

Sources & evidence

ORD record
ord-d835b3ac824a4cd9bcbcf22967fa7fd3
Source dataset
uspto-grants-2015_03
Patent number
US08980895B2

Reaction notes

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