HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-(Tetrahydropyran-2-yl)hydroxylamine → HCID 86671979, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-(Tetrahydropyran-2-yl)hydroxylamine | HCID 5142091 | — |
| Reactant | HCID 67071476 | HCID 67071476 | — |
| Product | HCID 86671979 | HCID 86671979 | — |
Reaction Steps
(+)-(E)-3-[1′-Benzyl-4-oxo-spiro(chromane-2,3′-pyrrolidine)-6-yl]-acrylic acid hydrochloride salt (33 mg, 0.083 mmol) was reacted with NH2OTHP following the procedure described in Example 1, Step C, giving (E)-3-[1′-benzyl-4-oxo-spiro(chromane-2,3′-pyrrolidine)-6-yl]-N-(tetrahydro-pyran-2-yloxy)-acrylamide (24 mg) as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08980877B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-789fa1c3ef66499d831801c090242f49 |
| Source note | uspto-grants-2015_03 |