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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 874253Generated: October 30, 2026

O-(Tetrahydropyran-2-yl)hydroxylamine → HCID 86671980, compound

https://huagongshe.com/reaction/874253

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-(Tetrahydropyran-2-yl)hydroxylamineHCID 5142091—
ReactantHCID 67071619HCID 67071619—
ProductHCID 86671980HCID 86671980—

Reaction Steps

(±)-(E)-3-[1′-Benzyl-4-oxo-spiro(chromane-2,3′-piperidine)-6-yl]-acrylic acid (250 mg, 0.604 mmol) was reacted with NH2OTHP following the procedure described in Example 12, Step C, giving (E)-3-[1′-benzyl-4-oxo-spiro(chromane-2,3′-piperidine)-6-yl]-N-(tetrahydro-pyran-2-yloxy)-acrylamide (270 mg) as a light yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08980877B2
Source datasetuspto-grants-2015_03
ORD IDord-97da3413856c46b3a65866079a355203
Source noteuspto-grants-2015_03