1-Bromo-6-(2-ethyl-6-methyl-phenoxy)-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester → 1-Cyano-6-(2-ethyl-6-methyl-phenoxy)-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester
Reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][C:6](=[O:7])[c:8]1[n:9][c:10]([Br:29])[c:11]2[cH:12][cH:13][c:14]([O:19][c:20]3[c:21]([CH2:27][CH3:28])[cH:22][cH:23][cH:24][c:25]3[CH3:26])[cH:15][c:16]2[c:17]1[OH:18].[Cu:30][C:31]#[N:32]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][C:6](=[O:7])[c:8]1[n:9][c:10]([C:31]#[N:32])[c:11]2[cH:12][cH:13][c:14]([O:19][c:20]3[c:21]([CH2:27][CH3:28])[cH:22][cH:23][cH:24][c:25]3[CH3:26])[cH:15][c:16]2[c:17]1[OH:18]Participants
3
Sources & evidence
- ORD record
- ord-28ed5f78ef124b92a82731650ac9331d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…