Water → HCID 178480426, compound

Participants

Reaction Steps

A mixture of Example 82c (0.09 g, 0.241 mmol), zinc dust (0.236 g, 3.62 mmol) and ammonium chloride (0.129 g, 2.411 mmol) in tetrahydrofuran (2.6 mL), ethanol (1.3 mL), and water (0.65 mL) was stirred at ambient temperature for 1 hour and then filtered to remove the solid. The filtrate was concentrated and then slurried in water. The solid was collected by filtration and dried in a vacuum oven at 70° C. to give 0.0732 g (88%) of the title compound as an impure mixture.

Provenance & Evidence