HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine, N,N-bis(2-chloroethyl)-p-methyl- → HCID 86715677, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine, N,N-bis(2-chloroethyl)-p-methyl- | HCID 19185 | — |
| Reactant | methyl (2S)-2-amino-3-{[(tert-butoxy)carbonyl]amino}propanoate hydrochloride | HCID 18334328 | — |
| Reactant | HCID 86715678 | HCID 86715678 | — |
| Product | HCID 86715677 | HCID 86715677 | — |
Reaction Steps
In a manner analogous to example 17.4, using 5.1 g (20 mmol) of commercial methyl (S)-2-amino-3-tert-butoxycarbonylaminopropanoate hydrochloride and 4.9 g (20 mmol) of bis(2-chloroethyl)(4-methylbenzyl)amine, 4.1 g (53%) of methyl (S)-3-tert-butoxycarbonylamino-2-(4-(4-methylbenzyl)piperazin-1-ylpropanoate are obtained in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08980897B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-d0960c66084a4db8ad18ad9995c41c2a |
| Source note | uspto-grants-2015_03 |