HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzoyl chloride → (2-chlorophenyl)-N-[5-(6-methyl(2,3-dihydrobenzo[b]furan-5-yl))(2-pyridyl)]carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzoyl chloride | HCID 69110 | — |
| Reactant | 5-(6-Methyl-2,3-dihydrobenzo[3,4-b]furan-5-yl)-2-pyridylamine | HCID 58487369 | — |
| Product | (2-chlorophenyl)-N-[5-(6-methyl(2,3-dihydrobenzo[b]furan-5-yl))(2-pyridyl)]carboxamide | HCID 58486962 | 59.8% |
Reaction Steps
Similarly, (2-chlorophenyl)-N-[5-(6-methyl(2,3-dihydrobenzo[b]furan-5-yl))(2-pyridyl)]carboxamide (164) (13.1 mg, yield: 59.8%, purity>95%) was prepared from 5-(6-methyl-2,3-dihydrobenzo[3,4-b]furan-5-yl)-2-pyridylamine (161) (13 mg, 0.06 mmol) and 2-chlorobenzoyl chloride (23 μl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08980629B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-7664ece7cbe741268ec5b2ec0f10281b |
| Source note | uspto-grants-2015_03 |