Aluminium lithium hydride → [5-(Hexadecyloxy)-1,3-phenylene]dimethanol

Participants

Reaction Steps

The product was generated using general protocol E using dimethyl-5-hexadecyloxyisophthalate (D10, 6.30 g), lithium aluminum hydride (1.27 g, 33.5 mmol), Et2O (150 mL) yielded 2.06 g (37.9%) of a white solid. 1H NMR (CDCl3, 400 MHz) δ: 6.93 (s, 1H, Ar—H), 6.85 (s, 2H, Ar—H), 4.67 (d, 3J=5.9 Hz, 4H, Ar—CH2—OH), 3.97 (t, 6.4 Hz, 2H, O—CH2), 1.78 (p, 3J=7.6 Hz, 2H, OCH2CH2), 1.66 (t, 3J=6.0 Hz, 2H, CH2—OH), 1.45 (p, 3J=7.6 Hz, 2H, O CH2CH2CH2), 1.26 (m, 24H), 0.88 (t, 3J=6.6, 3H, CH2—CH3).

Provenance & Evidence