2-(Methylamino)ethanol → 3-Formyl-N-(2-hydroxyethyl)-N-methylbenzamide

HRID 874816Notes

Reaction equation

HRID 874816 reaction equation
O1CC[O:3][CH:2]1[C:6]1[CH:7]=[C:8]([CH:13]=[CH:14][CH:15]=1)[C:9]([O:11]C)=O.[CH3:16][NH:17][CH2:18][CH2:19][OH:20].C(NCCO)C>>[CH:9]([C:8]1[CH:7]=[C:6]([CH:15]=[CH:14][CH:13]=1)[C:2]([N:17]([CH2:18][CH2:19][OH:20])[CH3:16])=[O:3])=[O:11]

Participants

4

Reactant 3

HCID 80162-(Methylamino)ethanolHCID 80722-(Ethylamino)ethanolHCID 19102594Methyl 3-(1,3-dioxolan-2-yl)benzoate

Product 1

HCID 867223063-Formyl-N-(2-hydroxyethyl)-N-methylbenzamide

Procedure

The title compound was prepared as described in Example 2 Step 2 with methyl 3-(1,3-dioxolan-2-yl)benzoate and N-methylethanolamine replacing methyl 4-(1,3-dioxolan-2-yl)benzoate and N-ethylethanolamine respectively.

Sources & evidence

ORD record
ord-b38135ccb2d440758f13b730ccecdd6b
Source dataset
uspto-grants-2015_03
Patent number
US08980913B2

Reaction notes

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