HCID 86722315, compound → HCID 86722316, compound

Participants

Reaction Steps

To a solution of 1-(2-hydroxyethyl)-3-(4-(hydroxymethyl)phenyl)-1-methylurea (0.50 g, 2.23 mmol) in DCM (30 mL) was added manganese (IV) oxide (0.78 g, 8.92 mmol). The reaction mixture was stirred at RT for 3 hours. The suspension was filtered through celite and the filter pad washed with further DCM. The filtrate was evaporated at reduced pressure to afford the title compound (0.23 g, 49%).

Provenance & Evidence