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HRID874909

反应详情

EQUATION

反应方程式

HRID 874909 的结构方程式

REACTANTS

反应物

3
结构：NCCN
HCID3301

Ethylenediamine

C2H8N2

结构：CCC(C)CC(C)CCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@H]([C@H](O)CC(N)=O)NC(=O)[C@H]([C@H](O)[C@@H](O)c2ccc(O)cc2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H]([C@@H](C)O)NC1=O
HCID5742645

未命名化合物

结构：[O-]B([O-])Oc1ccccc1
HCID19793864

未命名化合物

PRODUCTS

生成物

1
结构：CCC(C)CC(C)CCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@@H](NCCN)NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@H]([C@H](O)CCN)NC(=O)[C@H]([C@H](O)[C@@H](O)c2ccc(O)cc2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H]([C@@H](C)O)NC1=O
HCID2826718

Caspofungin

C52H88N10O15

PROCEDURE

实验过程

In CN101792486A and CN 101648994A, a method has been disclosed, comprising the following steps: Pneumocandin B0 as the starting material reacts with ethylenediamine under the protection of phenyl borate, and then the amide group in the resulting intermediate is reduced to amine group to obtain caspofungin.