3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 53327833, compound

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Reaction Steps

This compound was synthesized from 6-(2,2-dimethylpiperazin-1-yl)nicotinonitrile hydrochloride and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described for example 37 step 3 (50 mg, yield 33%). 1H NMR (400 MHz, MeOD) δ 8.43 (d, J=1.8 Hz, 1H), 8.29-8.22 (m, 2H), 7.75-7.72 (m, 3H), 6.88 (d, J=9.0 Hz, 1H), 4.05-3.85 (m, 4H), 3.67 (m, 2H), 1.67-1.47 (m, 6H). MS (ESI) m/z: Calculated for C22H19F3N6O2: 456.15. found: 457.2 (M+H)+

Provenance & Evidence