2-piperazin-1-yl-1H-benzoimidazole → (4-(1H-Benzo[d]imidazol-2-yl)piperazin-1-yl)(3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl)methanone

Participants

Reaction Steps

This compound was synthesized from 2-(piperazin-1-yl)-1H-benzo[d]imidazole and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described for example 37 step 3 (100 mg, yield 23%). 1H NMR (400 MHz, DMSO-d6) δ 11.49 (br s, 1H), 8.19-8.17 (d, J=8.5 Hz, 1H), 8.11 (s, 1H), 7.76-7.72 (m, 2H), 7.21 (m, 2H), 6.94 (m, 2H), 3.80 (m, 2H), 3.63-3.52 (m, 6H). MS (ESI) m/z: Calculated for C21H17F3N6O2: 442.14. found: 441.4 (M−H)−

Provenance & Evidence