Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 874999Generated: November 2, 2026

N-(3-methoxyphenyl)piperazine → HCID 53327887, compound

https://huagongshe.com/reaction/874999

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-methoxyphenyl)piperazineHCID 81430—
Reactant3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acidHCID 25180854—
ProductHCID 53327887HCID 5332788749%

Reaction Steps

This compound was synthesized from 1-(3-methoxyphenyl)piperazine and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described for example 37 step 3 (110 mg, yield 49%). 1H NMR (400 MHz, CDCl3) δ 8.22-8.20 (m, 2H), 7.67-7.60 (m, 2H), 7.23-7.19 (m, 1H), 6.57-6.54 (m, 1H), 6.49-6.48 (m, 2H), 3.98 (m, 2H), 3.80 (s, 3H), 3.61 (m, 2H), 3.30-3.16 (m, 4H). MS (ESI) m/z: Calculated for C21H18F3N4O3: 432.14. found: 433.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08981084B2
Source datasetuspto-grants-2015_03
ORD IDord-2493e63bb04d43bcb1ca00119c585413
Source noteuspto-grants-2015_03