Trifluoroacetate → HCID 86673537, compound

HRID 875001Notes

Reaction equation

HRID 875001 reaction equation
[N:1]1[CH:6]=[C:5]([N:7]2[CH2:12][CH2:11][N:10](C(OC(C)(C)C)=O)[CH2:9][CH2:8]2)[CH:4]=[N:3][CH:2]=1.[F:20][C:21]([F:26])([F:25])[C:22]([O-:24])=[O:23]>>[OH:24][C:22]([C:21]([F:26])([F:25])[F:20])=[O:23].[N:7]1([C:5]2[CH:4]=[N:3][CH:2]=[N:1][CH:6]=2)[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]1

Participants

3

Reactant 2

HCID 84468TrifluoroacetateHCID 67325143tert-Butyl 4-(pyrimidin-5-yl)piperazine-1-carboxylate

Product 1

HCID 86673537HCID 86673537, compound

Procedure

This compound was synthesized from tert-butyl 4-(pyrimidin-5-yl)piperazine-1-carboxylate as described for example 46 step 4 (500 mg, crude) as a trifluoroacetate salt and it was carried through without further purification. MS (ESI) m/z: Calculated for C8H12N4: 164.11. found: 165.0 (M+H)+

Workup

  1. customwas carried through without further purification

Sources & evidence

ORD record
ord-622d5146aa8d4e0889992c3e087d2123
Source dataset
uspto-grants-2015_03
Patent number
US08981084B2

Reaction notes

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