2-(Piperazin-1-yl)pyridine-3-carbonitrile → HCID 53327903, compound

Participants

Reaction Steps

This compound was synthesized from 2-(piperazin-1-yl)nicotinonitrile and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described for example 37 step 3 (135 mg, yield 81%). 1H NMR (400 MHz, DMSO-d6) δ 8.45-8.43 (dd, J=4.8 Hz, 1.8 Hz, 1H), 8.18-8.15 (dd, J=7.3 Hz, 1.6 Hz, 1H), 8.13-8.10 (m, 2H), 7.78-7.71 (m, 2H), 6.99-6.96 (dd, J=7.5 Hz, 4.8 Hz, 1H), 3.81-3.75 (m, 4H), 3.63-3.54 (m, 4H). MS (ESI) m/z: Calculated for C20H15F3N6O2: 428.12. found: 429.1 (M+H)+

Provenance & Evidence