反应详情

This compound was synthesized from 2-(piperazin-1-yl)benzo[d]oxazole and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described for example 37 step 3 (20 mg, yield 12%). 1H NMR (400 MHz, CDCl3) δ 8.26-8.22 (m, 2H), 7.69-7.63 (m, 2H), 7.40-7.39 (m, 1H), 7.31-7.29 (m, 1H), 7.23-7.19 (td, J=7.7 Hz, 1.1 Hz, 1H), 7.10-7.06 (m, 1H), 3.96-3.63 (m, 8H). MS (ESI) m/z: Calculated for C21H16F3N5O3: 443.12. found: 444.2 (M+H)+