Trifluoroacetate → HCID 86673540, compound

HRID 875026Notes

Reaction equation

HRID 875026 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:9][CH:10]=[C:11]([CH2:13][N:14]3[CH2:19][CH2:18][N:17](C(OC(C)(C)C)=O)[CH2:16][CH2:15]3)[N:12]=2)=[CH:4][CH:3]=1.[F:27][C:28]([F:33])([F:32])[C:29]([O-:31])=[O:30]>>[OH:31][C:29]([C:28]([F:33])([F:32])[F:27])=[O:30].[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:9][CH:10]=[C:11]([CH2:13][N:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[N:12]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 84468TrifluoroacetateHCID 70975537HCID 70975537, compound

Product 1

HCID 86673540HCID 86673540, compound

Procedure

This compound was synthesized from tert-butyl 4-((2-(4-fluorophenyl)thiazol-4-yl)methyl)piperazine-1-carboxylate as described for example 46 step 4 (43 mg, crude) as a trifluoroacetate salt and it was carried through without further purification. MS (ESI) m/z: Calculated for C14H16FN3S: 277.10. found: 278.1 (M+H)+

Workup

  1. customwas carried through without further purification

Sources & evidence

ORD record
ord-868a8f34615048c8b92f21be57162317
Source dataset
uspto-grants-2015_03
Patent number
US08981084B2

Reaction notes

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