Trifluoroacetate → HCID 86673542, compound

HRID 875035Notes

Reaction equation

[C:1]1([C:7]2[S:8][CH:9]=[C:10]([C:12]([N:14]3[CH2:19][CH2:18][N:17](C(OC(C)(C)C)=O)[CH2:16][CH2:15]3)=[O:13])[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:27][C:28]([F:33])([F:32])[C:29]([O-:31])=[O:30]>>[OH:31][C:29]([C:28]([F:33])([F:32])[F:27])=[O:30].[C:1]1([C:7]2[S:8][CH:9]=[C:10]([C:12]([N:14]3[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]3)=[O:13])[N:11]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

Reactant 2

HCID 84468Trifluoroacetate

HCID 46684680HCID 46684680, compound

Product 1

HCID 86673542HCID 86673542, compound

Procedure

This compound was synthesized from tert-butyl 4-(2-phenylthiazole-4-carbonyl)piperazine-1-carboxylate as described for example 46 step 4 (300 mg, crude) as trifluoroacetate salt and it was taken as such for the next step. MS (ESI) m/z: Calculated for C14H15N3OS: 273.09. found: 274.0 (M+H)+

Sources & evidence

ORD record: ord-a47de0478a8e4a738ae035702f5b51d8
Source dataset: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08981084B2

Reaction notes

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