3-(5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid → HCID 69935727, compound

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Reaction Steps

This compound was synthesized from (1S,4S)-2-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane TFA salt and 3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzoic acid as described for example 37 step 3 (30 mg, yield 27%). 1H NMR (400 MHz, CDCl3) δ8.28-8.07 (m, 3H), 7.74-7.71 (m, 1H), 7.65-7.43 (m, 2H), 6.66-6.55 (m, 1H), 6.45-6.33 (m, 1H), 5.16-4.94 (m, 2H), 3.82-3.49 (m, 4H), 2.10-2.05 (m, 2H). MS (ESI) m/z: Calculated for C20H16F3N5O2: 415.13. found: 416.2 (M+H)+

Provenance & Evidence