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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 875040Generated: October 30, 2026

(1R,2R)-2-Carbamoyl-cyclohexanecarboxylic acid → ((1R,2R)-2-(aminomethyl)cyclohexyl)methanol

https://huagongshe.com/reaction/875040

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,2R)-2-Carbamoyl-cyclohexanecarboxylic acidHCID 6928785—
ReactantSodium borohydride boron trifluoride etherateHCID 131732581—
Product((1R,2R)-2-(aminomethyl)cyclohexyl)methanolHCID 15247349—

Reaction Steps

((1R,2R)-2-(aminomethyl)cyclohexyl)methanol was prepared by reduction of enantiomerically pure trans-1,2-cyclohexanedicarboxylic acid monoamide using sodium borohydride-boron trifluoride etherate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08981095B2
Source datasetuspto-grants-2015_03
ORD IDord-a803f1d50ab2499ca74bb3cb91d7b8c6
Source noteuspto-grants-2015_03