Ammonia → tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanimidoyl)carbamate

Participants

Reaction Steps

15 g of 1,3-bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea (0.052 mol) were suspended in 150 mL of gaseous ammonia in methanol and the mixture was stirred at room temperature in a close bottle at room temperature. The resulting solution was concentrated in vacuo until 10 g (74% yield) of the title compound precipitated which were collected by filtration.

Provenance & Evidence