Pyridine → HCID 42598816, compound

Participants

Reaction Steps

Compound of example 2 (150 mg, 0.531 mmole) was dissolved in dichloromethane (10 mL). Acetic anhydride (54.25 mg, 0.531 mmole), pyridine (84 mg, 1.062 mmole) and 4-(dimethylamino)-pyridine (DMAP) (2 mg) were added to this solution and reaction mixture was stirred for 30 minutes. Reaction mixture was extracted with dichloromethane (3×100 mL). The dichloromethane layer was washed with water and brine and was dried over sodium sulfate. The solvent was removed and crude product was purified by crystallization using ethyl acetate/petroleum ether to obtain the title compound.

Provenance & Evidence