Pyridine → HCID 42600050, compound

Participants

Reaction Conditions

Reaction Steps

Compound of example 38 (200.0 mg, 0.39 mmol) was dissolved in DCM (10 mL). To it was added acetic anhydride (43.86 mg, 0.43 mmol), pyridine (61.70 mg, 0.78 mmol) and DMAP (2 mg) and reaction mixture was stirred at room temperature (25° C.) for 2 hours. Reaction mixture was diluted with water and extracted with DCM (3×50 mL). The crude product was purified by column chromatography (silica gel, 40% ethyl acetate in petroleum ether) to obtain the title compound.

Provenance & Evidence