Acetic Anhydride → HCID 42600544, compound

Participants

Reaction Conditions

Reaction Steps

The compound obtained in step 1 of example 55 (200 mg, 0.389 mmole) was dissolved in dry acetonitrile (4 mL) and to it acetic anhydride (43.78 mg, 0.426 mmole) and TEA (59.04 mg, 0.58 mmole) were added. The reaction mixture was stirred at room temperature (25° C.) for 2 hours. Reaction mixture was concentrated and crude product was purified by column chromatography (silica gel, 30% ethyl acetate in petroleum ether) to obtain the title compound.

Provenance & Evidence