6-Azaindole → 3,5-Dichloro-N-ethyl-4-(1H-pyrrolo[2,3-c]pyridin-3-ylcarbonyl)benzamide

HRID 875425Notes

Reaction equation

HRID 875425 reaction equation
[NH:1]1[C:5]2=[CH:6][N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[CH:2]1.[Cl:10][C:11]1[CH:16]=[C:15]([C:17](=[O:21])[NH:18][CH2:19][CH3:20])[CH:14]=[C:13]([Cl:22])[C:12]=1[C:23](Cl)=[O:24]>>[Cl:10][C:11]1[CH:16]=[C:15]([CH:14]=[C:13]([Cl:22])[C:12]=1[C:23]([C:3]1[C:4]2[C:5](=[CH:6][N:7]=[CH:8][CH:9]=2)[NH:1][CH:2]=1)=[O:24])[C:17]([NH:18][CH2:19][CH3:20])=[O:21]

Participants

3

Reactant 2

HCID 92196-AzaindoleHCID 867206352,6-Dichloro-4-(ethylcarbamoyl)benzene carbonyl chloride

Product 1

HCID 716182323,5-Dichloro-N-ethyl-4-(1H-pyrrolo[2,3-c]pyridin-3-ylcarbonyl)benzamide

Procedure

3,5-Dichloro-N-ethyl-4-(1H-pyrrolo[2,3-c]pyridin-3-ylcarbonyl)benzamide was prepared from 1H-Pyrrolo[2,3-c]pyridine and 2,6-dichloro-4-(ethylcarbamoyl)benzene carbonyl chloride (Compound No. 2).

Sources & evidence

ORD record
ord-205f95496b4e4730a954f23fde14fbea
Source dataset
uspto-grants-2015_03
Patent number
US08980911B2

Reaction notes

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