2-Chloro-6-fluorobenzoyl chloride → HCID 86720644, compound

HRID 875436Notes

Reaction equation

HRID 875436 reaction equation
[NH:1]1[C:5]2=[C:6]([NH:10][C:11](=[O:14])[CH2:12][CH3:13])[N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[CH:2]1.[Cl:15][C:16]1[CH:24]=[CH:23][CH:22]=[C:21]([F:25])[C:17]=1[C:18](Cl)=[O:19]>>[Cl:15][C:16]1[CH:24]=[CH:23][CH:22]=[C:21]([F:25])[C:17]=1[C:18]([C:3]1[C:4]2[C:5](=[C:6]([NH:10][C:11](=[O:14])[CH2:12][CH3:13])[N:7]=[CH:8][CH:9]=2)[NH:1][CH:2]=1)=[O:19]

Participants

3

Reactant 2

HCID 27365472-Chloro-6-fluorobenzoyl chlorideHCID 86720621HCID 86720621, compound

Product 1

HCID 86720644HCID 86720644, compound

Procedure

N-[3-(2-Chloro-6-fluorobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]propanamide was synthesized using N-(1H-pyrrolo[2,3-c]pyridin-7-yl)propanamide and 2-chloro-6-fluoro benzoyl chloride (Compound No. 28).

Sources & evidence

ORD record
ord-a713b381f42d4bcfb1016b014251d71a
Source dataset
uspto-grants-2015_03
Patent number
US08980911B2

Reaction notes

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