2,6-Dichloro-4-cyanobenzoyl chloride → HCID 86720650, compound

HRID 875448Notes

Reaction equation

HRID 875448 reaction equation
[NH:1]1[C:5]2=[C:6]([NH:10][C:11](=[O:13])[CH3:12])[N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[CH:2]1.[C:14]([C:16]1[CH:24]=[C:23]([Cl:25])[C:19]([C:20](Cl)=[O:21])=[C:18]([Cl:26])[CH:17]=1)#[N:15]>>[Cl:25][C:23]1[CH:24]=[C:16]([C:14]#[N:15])[CH:17]=[C:18]([Cl:26])[C:19]=1[C:20]([C:3]1[C:4]2[C:5](=[C:6]([NH:10][C:11](=[O:13])[CH3:12])[N:7]=[CH:8][CH:9]=2)[NH:1][CH:2]=1)=[O:21]

Participants

3

Reactant 2

HCID 866489562,6-Dichloro-4-cyanobenzoyl chlorideHCID 86720620N-(1H-Pyrrolo[2,3-c]pyridin-7-yl)acetamide

Product 1

HCID 86720650HCID 86720650, compound

Procedure

N-[3-(2,6-Dichloro-4-cyanobenzoyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]acetamide (Compound No. 21) was prepared from N-(1H-pyrrolo[2,3-c]pyridin-7-yl)acetamide and 4-cyano-2,6-dichloro benzoyl chloride.

Sources & evidence

ORD record
ord-cc1dee27009c41d29d48e4ae09509097
Source dataset
uspto-grants-2015_03
Patent number
US08980911B2

Reaction notes

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