5-Azaindole → HCID 71618549, compound

HRID 875463Notes

Reaction equation

HRID 875463 reaction equation
[NH:1]1[C:9]2[CH:8]=[CH:7][N:6]=[CH:5][C:4]=2[CH:3]=[CH:2]1.[Cl:10][C:11]1[CH:19]=[C:18]([C:20](=[O:25])[NH:21][CH2:22][C:23]#[N:24])[CH:17]=[C:16]([Cl:26])[C:12]=1[C:13](O)=[O:14]>>[Cl:10][C:11]1[CH:19]=[C:18]([CH:17]=[C:16]([Cl:26])[C:12]=1[C:13]([N:1]1[C:9]2[CH:8]=[CH:7][N:6]=[CH:5][C:4]=2[CH:3]=[CH:2]1)=[O:14])[C:20]([NH:21][CH2:22][C:23]#[N:24])=[O:25]

Participants

3

Reactant 2

HCID 92205-AzaindoleHCID 86720657HCID 86720657, compound

Product 1

HCID 71618549HCID 71618549, compound

Procedure

3,5-Dichloro-N-(cyanomethyl)-4-(1H-pyrrolo[3,2-c]pyridin-1-ylcarbonyl)benzamide (Compound No. 76) was prepared using 1H-pyrrolo[3,2-c]pyridine and 2,6-dichloro-4-[(cyanomethyl)carbamoyl]benzoic acid.

Sources & evidence

ORD record
ord-5be38b75e47648adae0fe4dc922cd39f
Source dataset
uspto-grants-2015_03
Patent number
US08980911B2

Reaction notes

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