5-Azaindole → [2,6-Dichloro-4-(hydroxymethyl)phenyl](1H-pyrrolo[3,2-c]pyridin-1-yl)methanone

HRID 875468노트

반응식

HRID 875468 반응식
[NH:1]1[C:9]2[CH:8]=[CH:7][N:6]=[CH:5][C:4]=2[CH:3]=[CH:2]1.[Cl:10][C:11]1[CH:19]=[C:18]([CH2:20][OH:21])[CH:17]=[C:16]([Cl:22])[C:12]=1[C:13](O)=[O:14]>>[Cl:10][C:11]1[CH:19]=[C:18]([CH2:20][OH:21])[CH:17]=[C:16]([Cl:22])[C:12]=1[C:13]([N:1]1[C:9]2[CH:8]=[CH:7][N:6]=[CH:5][C:4]=2[CH:3]=[CH:2]1)=[O:14]

참가 물질

3

반응물 2

HCID 92205-AzaindoleHCID 667205832,6-Dichloro-4-(hydroxymethyl)benzoic acid

생성물 1

HCID 71618612[2,6-Dichloro-4-(hydroxymethyl)phenyl](1H-pyrrolo[3,2-c]pyridin-1-yl)methanone

실험 절차

[2,6-Dichloro-4-(hydroxymethyl)phenyl](1H-pyrrolo[3,2-c]pyridin-1-yl)methanone (Compound No. 90) was synthesized from N-(1H-pyrrolo[3,2-c]pyridine and 2,6-dichloro-4-(hydroxymethyl)benzoic acid.

출처 및 근거

ORD 기록
ord-a6e5a101f329421297fc4e492ede5e2a
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08980911B2

반응 노트

불러오는 중…