Methyl chloroformate → HCID 86720660, compound

HRID 875473Notes

Reaction equation

HRID 875473 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([C:9]([N:11]2[C:19]3[CH:18]=[CH:17][N:16]=[CH:15][C:14]=3[CH:13]=[CH:12]2)=[O:10])=[C:4]([Cl:20])[CH:3]=1.[CH3:21][O:22][C:23](Cl)=[O:24].ClC1C=CC=C(Cl)C=1C(N1C2C=CN=C(NC(=O)OC)C=2C=C1)=O>>[Cl:8][C:6]1[CH:7]=[C:2]([NH:1][C:23](=[O:24])[O:22][CH3:21])[CH:3]=[C:4]([Cl:20])[C:5]=1[C:9]([N:11]1[C:19]2[CH:18]=[CH:17][N:16]=[CH:15][C:14]=2[CH:13]=[CH:12]1)=[O:10]

Participants

4

Reactant 3

HCID 6586Methyl chloroformateHCID 86720656HCID 86720656, compoundHCID 86720659HCID 86720659, compound

Product 1

HCID 86720660HCID 86720660, compound

Procedure

Methyl [3,5-dichloro-4-(1H-pyrrolo[3,2-c]pyridin-1-ylcarbonyl)phenyl]carbamate (Compound No. 79) was prepared by treating (4-amino-2,6-dichlorophenyl)(1H-pyrrolo[3,2-c]pyridin-1-yl)methanone with methylchloroformate following a procedure similar to the one used for methyl [1-(2,6-dichlorobenzoyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]carbamate (Compound No. 74).

Sources & evidence

ORD record
ord-6f01fd392f404313a5b8de8ecd1e6777
Source dataset
uspto-grants-2015_03
Patent number
US08980911B2

Reaction notes

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