HCID 71061298, compound → HCID 86720664, compound
Reaction equation
[NH2:1][C:2]1[C:7]([C:8]#[C:9][Si:10]([CH3:13])([CH3:12])[CH3:11])=[CH:6][N:5]=[C:4](C#N)[CH:3]=1.IC1C(N)=CC([NH:23][C:24]([CH3:31])([CH2:26][C:27]([CH3:30])([CH3:29])[CH3:28])[CH3:25])=NC=1>>[CH3:25][C:24]([NH:23][C:4]1[CH:3]=[C:2]([NH2:1])[C:7]([C:8]#[C:9][Si:10]([CH3:11])([CH3:12])[CH3:13])=[CH:6][N:5]=1)([CH2:26][C:27]([CH3:30])([CH3:29])[CH3:28])[CH3:31]Participants
3
Procedure
The compound was prepared following the procedure same as that of 4-amino-5-[(trimethylsilyl)ethynyl]pyridine-2-carbonitrile starting from 5-iodo-N2-(2,4,4-trimethylpentan-2-yl)pyridine-2,4-diamine.
Workup
- customThe compound was prepared
Sources & evidence
- ORD record
- ord-aaf995f8c7054524aeb58a127a9fbc70
- Source dataset
- uspto-grants-2015_03
- Patent number
- US08980911B2
Reaction notes
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