1H-Pyrrolo[3,2-c]pyridine-6-carbonitrile → HCID 86720665, compound
Reaction equation
N1C2C=C(C#N)N=CC=2C=C1.[CH3:12][C:13]([NH:20][C:21]1[CH:26]=[C:25]([NH2:27])[C:24]([C:28]#[C:29][Si](C)(C)C)=[CH:23][N:22]=1)([CH2:15][C:16]([CH3:19])([CH3:18])[CH3:17])[CH3:14]>>[CH3:12][C:13]([NH:20][C:21]1[N:22]=[CH:23][C:24]2[CH:28]=[CH:29][NH:27][C:25]=2[CH:26]=1)([CH2:15][C:16]([CH3:19])([CH3:18])[CH3:17])[CH3:14]Participants
3
Procedure
The compound was prepared following the procedure same as that of 1H-pyrrolo[3,2-c]pyridine-6-carbonitrile starting from N2-(2,4,4-trimethylpentan-2-yl)-5-[(trimethylsilyl)ethynyl]pyridine-2,4-diamine.
Workup
- customThe compound was prepared
Sources & evidence
- ORD record
- ord-4bdc8c14d3b64f6ab941b2e9fd96350a
- Source dataset
- uspto-grants-2015_03
- Patent number
- US08980911B2
Reaction notes
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