HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 3-Hydroxy-3-(3-(isopentyloxy)phenyl)propanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 3-(3-Methylbutoxy)benzaldehyde | HCID 28065613 | — |
| Product | 3-Hydroxy-3-(3-(isopentyloxy)phenyl)propanenitrile | HCID 67316645 | — |
Reaction Steps
Addition of acetonitrile to 3-(isopentyloxy)benzaldehyde gave 3-hydroxy-3-(3-(isopentyloxy)phenyl)propanenitrile as a yellow oil. Yield (0.82 g, 54%): 1H NMR (400 MHz, CDCl3) δ 7.27-7.32 (m, 1H), 6.94-6.96 (m, 2H), 6.85-6.90 (m, 1H), 5.00-5.03 (m, 1H), 3.99 (t, J=6.4 Hz, 2H), 2.77 (d, J=6.0 Hz, 2H), 1.81-1.88 (m, 1H), 1.64-1.71 (m, 2H), 0.96 (d, J=6.4 Hz, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08981153B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-115494363b3c48bc98b0702e72108cf1 |
| Source note | uspto-grants-2015_03 |