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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 875587Generated: October 25, 2026

Acetonitrile → 3-Hydroxy-3-(3-(2-hydroxy-2-phenylethoxy)phenyl)propanenitrile

https://huagongshe.com/reaction/875587

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
Reactant3-(2-Hydroxy-2-phenylethoxy)benzaldehydeHCID 60708533—
Product3-Hydroxy-3-(3-(2-hydroxy-2-phenylethoxy)phenyl)propanenitrileHCID 67317027—

Reaction Steps

Addition of acetonitrile to 3-(2-hydroxy-2-phenylethoxy)benzaldehyde gave 3-hydroxy-3-(3-(2-hydroxy-2-phenylethoxy)phenyl)propanenitrile as a yellow oil. Yield (0.97 g, crude): MS: 284 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08981153B2
Source datasetuspto-grants-2015_03
ORD IDord-6e6def26891347e1b31ac9b6d1f780ae
Source noteuspto-grants-2015_03