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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 87607Generated: October 27, 2026

Formaldehyde → tert-Butyl alpha-(1-Hydroxymethyl)-3-(2-methylpropyl)-2-oxo-1-(2-phenylethyl)-3-pyrrolidineacetate

https://huagongshe.com/reaction/87607

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantDiisopropylamideHCID 5062348—
Reactanttert-Butyl 3-(2-Methylpropyl)-2-oxo-1-(2-phenylethyl)-3-pyrrolidineacetateHCID 54164883—
Producttert-Butyl alpha-(1-Hydroxymethyl)-3-(2-methylpropyl)-2-oxo-1-(2-phenylethyl)-3-pyrrolidineacetateHCID 19705491—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-b16a4b99040449f2bd444b93e1b1dc96
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)