Methyl pyrrole-2-carboxylate → HCID 70675089, compound

HRID 876082Notes

Reaction equation

HRID 876082 reaction equation
[F:1][CH2:2][N:3]1[CH:7]=[CH:6][CH:5]=[C:4]1[C:8]1[O:12][C:11](S)=[N:10][N:9]=1.F[CH2:15][N:16]1[CH:20]=[CH:19][CH:18]=[C:17]1[C:21]([NH:23]N)=O.F[CH2:26]N1C=CC=C1C(OC)=O.N1C=CC=C1C(OC)=O>>[N:16]12[CH2:20][CH2:19][CH:18]([CH2:26][CH2:15]1)[N:23]([C:11]1[O:12][C:8]([C:4]3[N:3]([CH2:2][F:1])[CH:7]=[CH:6][CH:5]=3)=[N:9][N:10]=1)[CH2:21][CH2:17]2

Participants

5

Reactant 4

HCID 136930Methyl pyrrole-2-carboxylateHCID 86709241HCID 86709241, compoundHCID 86709242HCID 86709242, compoundHCID 178506413HCID 178506413, compound

Product 1

HCID 70675089HCID 70675089, compound

Procedure

May be prepared according to Methods A-D from 5-[1-(fluoromethyl)pyrrol-2-yl]-1,3,4-oxadiazole-2-thiol (Method A), from 1-(fluoromethyl)pyrrole-2-carbohydrazide (Method B), from methyl 1-(fluoromethyl)pyrrole-2-carboxylate (Method C), and from methyl 1H-pyrrole-2-carboxylate (Method D).

Workup

  1. customMay be prepared

Sources & evidence

ORD record
ord-5dc9b6964e3d43c58803ce21518621fb
Source dataset
uspto-grants-2015_03
Patent number
US08986654B2

Reaction notes

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