Ethylenediamine → HCID 17854996, compound

Participants

Reaction Conditions

Reaction Steps

In a 500 mL, 3-necked round-bottomed flask were taken 5.31 grams of 1,2-ethylenediamine and 32.48 g of anhydrous potassium carbonate, and 300 mL of chloroform. To this suspension was added 30 g of 4-vinylbenzyl chloride. The resulting reaction mixture was stirred at 25° C. for 18 hr. Subsequently the reaction mixture was filtered. The solvent was moved under reduced pressure. To the residue was added 300 mL of deionized water followed by 37% aqueous HCl until the pH of the solution was 2.0. The resulting aqueous solution was extracted with tert-butyl methyl ether (2×250 mL). The aqueous layer was collected and was treated with 40% (w/w) NaOH until the pH of the solution was 11.4. The resulting aqueous solution was extracted with tert-butyl methyl ether (2×250 mL). The organic layers were combined and dried over anhydrous sodium sulfate. After filtration, the solvent was removed under reduced pressure yielding 3 g of the product as a light yellow oil.

Provenance & Evidence