Cyclohexylamine → HCID 53261096, compound

Participants

Reaction Conditions

Reaction Steps

78 mg of 6-chloro-N-(4-morpholinophenyl)pyrimidin-4-amine, 55 mg of cyclohexylamine and 72 mg if DIPEA were dissolved in 2 mL of n-BuOH and the mixture obtained was charged into a microwave vial and the vial obtained was heated to 200° C. for 90 minutes under microwave irradiation. Upon evaporation of n-BuOH a precipitate formed and was subjected to crystallization from n-BuOH-EtOH solvent mixture. N4-Cyclohexyl-N6-(4-morpholinophenyl)pyrimidine-4,6-diamine was obtained in the form of a colorless solid.

Provenance & Evidence